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Why do people hesitate to use an EpiPen?

Short answer

Fear of the needle, not being sure the reaction is serious enough, and worry about using it wrong. Canadian research shows many people with an auto-injector don't use it before hospital. Practice with a trainer, a clear emergency plan, and step-by-step instructions all help.

A study of 483 food-induced anaphylaxis cases at nine Canadian emergency departments found that only 41% of people who had an auto-injector with them used it before reaching hospital. At the CSACI meeting in October 2026, a Western University team working on patient education mapped what gets in the way, from meetings with patients, caregivers and clinic staff and a review of the research: anxiety or fear about using the device, not knowing the symptoms well, lack of practice, and mistakes such as accidentally removing the blue safety cap or pulling the injector away before the full dose was delivered.

Confidence can be built. The same team is testing a short educational video, and its early, self-reported results look encouraging, though the data are still being analysed. Practise with a trainer, keep your emergency plan with the epinephrine, and brief every caregiver.

A ResQBand Tap Card puts the maker's steps on the helper's own phone at the moment they're needed: tapped with most phones, it says to use the epinephrine now and call 911.

Sources

  1. Epinephrine underused during anaphylaxis outside of hospital (Gabrielli et al., JACI: In Practice), McGill University Health Centre (2018)
  2. Poster: Short-form TikTok videos for patient education: improving understanding of anaphylaxis and epinephrine autoinjector use (Moersch A, et al.; Western University), 81st CSACI Annual Scientific Meeting, Toronto (2026)
  3. Poster: Greater willingness to use nasal epinephrine spray versus epinephrine autoinjector in a Canadian comparative study (Dua S, Mack DP, et al.), 81st CSACI Annual Scientific Meeting, Toronto (2026)
  4. 81st Annual CSACI Scientific Meeting, Toronto, October 15 to 18, 2026, Canadian Society of Allergy and Clinical Immunology (2026)

Fact-checked by Western Allergy Services Ltd., Canadian allergy company since 1972, on October 22, 2026. Last updated October 22, 2026. How we check our answers

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General information, not medical advice. Always follow the instructions that come with your medication and the advice of your pharmacist or doctor. In an emergency, call 911. Medical disclaimer